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Celiac Disease Treatment Market Analysis

The Celiac Disease Treatment Market size is estimated at USD 634.69 million in 2024, and is expected to reach USD 874.89 million by 2029, growing at a CAGR of 6.63% during the forecast period (2024-2029).

Celiac disease triggers an immune attack on the small intestine due to gluten commonly found in wheat, barley, and rye. This damages the gut lining and hinders nutrient absorption. The symptoms include bloating, diarrhea, and malnutrition. Hence, a strict gluten-free diet is the main treatment. Currently, there are no medications available to treat celiac disease, only symptomatic treatment. The key growth drivers include the rising prevalence of celiac disease, the development of novel therapies, and growing awareness of celiac disease.

The prevalence of celiac disease is increasing globally, which increases the need for treatment products. For instance, according to a study published in Gastroenterology in February 2024, celiac disease is a widespread lifelong disorder affecting 0.7% to 2.9% of the general population globally. Similarly, according to a study published in Gastroenterology in October 2023, the condition's incidence in Colorado, Washington, and Sweden was as high as 2.4%, 0.9%, and 3%, respectively, in 2022. In these regions, the number of people suffering from celiac disease is increasing. Thus, the increase in the incidence rates of celiac disease is expected to drive the market over the next five years.

The focus on an immune tolerance-based therapy signifies a potential shift in treatment goals. For instance, in May 2023, Topas Therapeutics commenced a Phase IIa clinical trial for TPM502 for the treatment of celiac disease. This trial investigates TPM502's ability to induce immune tolerance, potentially allowing patients to consume gluten without adverse effects. The introduction of TPM502 signifies a significant advancement in the immune tolerance-based clinical pipeline and reflects the commitment to offering innovative disease-modifying therapeutics to patients with limited pharmacological options. Thus, the constant research to develop the treatment for celiac disease is growing and is expected to drive the demand for celiac disease treatment over the next five years.

The market will likely continue to grow based on the increasing demand for improved treatment options and the growing prevalence of celiac disease. However, limited treatment options and challenges in accurately diagnosing celiac disease restrain market growth.

Celiac Disease Treatment Market Trends

The Segment for Refractory Celiac Disease is Expected to Witness Significant Growth Over the Forecast Period

Celiac Disease Treatment Industry Segmentation

People with celiac disease have a variety of nutritional concerns. Gluten, a protein naturally found in certain grains like wheat, barley, rye, and some oats, triggers an autoimmune response that causes inflammation and damages the small intestine's lining. This damage can lead to abnormal digestion and reduced nutrient absorption. There are two types of celiac disease: Type I (RCeDI), which might be driven by an extreme sensitivity to gluten traces, and Type II (RCeDII), which is a severe form associated with a higher risk of cancer. The main treatment is to opt for a gluten-free diet and treatment plans.

The celiac disease treatment market is segmented by product type, type, treatment type, distribution channel, and geography. By product type, the market is segmented into vitamin and mineral supplements, steroids, and immunosuppressive drugs. By type, the market is segmented into non-responsive celiac disease and refractory celiac disease. By treatment, the market is segmented into first line and second line. By distribution channel, the market is segmented into hospital pharmacy, retail pharmacy, online pharmacy, and others, including home care settings and specialty clinics. By geography, the market is segmented into North America, Europe, Asia-Pacific, Middle East and Africa, and South America. The report also offers the market sizes and forecasts for 17 countries across the region. For each segment, the market sizing and forecasts were made on the basis of value (USD).