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Intravenous Immunoglobulin (IVIG) Market Analysis

The intravenous immunoglobulin market is expected to register a CAGR of 7.13% over the forecast period, 2022-2027.

The outbreak of the COVID-19 pandemic, in its latter phase, is likely to positively impact the intravenous immunoglobulin market's growth. According to an article titled "COVID-19 in patients with primary and secondary immunodeficiency: The United Kingdom experience" published in December 2020, the study revealed that out of 100 individuals with primary immunodeficiency (PID), symptomatic secondary immunodeficiency (SID), autoinflammatory diseases, and C1 inhibitor deficiency, 70% of the individuals were infected with the SARS-CoV-2 virus, and 59% were admitted to hospitals, with 8% being admitted to intensive care units. Thus, immune-deficient individuals are at a higher risk of being infected with COVID-19, so the market for intravenous immunoglobulin therapies is expected to grow during the pandemic. Additionally, as per an October 2020 published article titled, "The use of Intravenous Immunoglobulin Gamma for the treatment of severe coronavirus disease 2019: a randomized placebo-controlled double-blind clinical trial," the administration of intravenous immunoglobulin in patients with severe COVID-19 infection was expected to improve the clinical outcome and aid in a significant reduction of the mortality rate due to SARS-CoV2 viral infection. Thus, the studied market is expected to witness healthy growth during the pandemic due to the above factors.

Further, the significant factors fueling the market's growth are the rise in the geriatric population, the increase in the adoption of immunoglobulin treatment, and the growing prevalence of immunodeficiency diseases and bleeding disorders.

The increasing adoption of immunoglobulin with product launches and approvals is likely to boost the market's growth in the future. For instance, in June 2022, Amgen received United States Food and Drug Administration (FDA) approval for RIABNI (rituximab-arrx), a biosimilar to Rituxan, in combination with methotrexate for adults with moderate to severely active rheumatoid arthritis (RA) who have had an inadequate response to one or more tumor necrosis factor (TNF) antagonist therapies.

Additionally, in December 2021, the United States Food and Drug Administration approved Vyvgart (efgartigimod) to Argenx BV for the treatment of generalized myasthenia gravis (gMG) in adults who test positive for the anti-acetylcholine receptor (AChR) antibody. Thus, the market is expected to witness significant growth over the forecast period due to the abovementioned factors. However, stringent government regulations and the high cost of therapy may hinder the growth of the market.

Intravenous Immunoglobulin (IVIG) Industry Segmentation

As per the scope of this report, intravenous immunoglobulin (IVIG) therapy is the use of a mixture of antibodies (immunoglobulins) to treat health conditions, including primary immunodeficiency, immune thrombocytopenic purpura, chronic inflammatory demyelinating polyneuropathy, Kawasaki disease, certain cases of HIV/AIDS, measles, Guillain-Barré syndrome, and certain other infections. Depending on the formulation, it can be injected into a muscle, a vein, or under the skin. The intravenous immunoglobulin market is segmented by type (IgG, IgA, IgM, IgE, and IgD), application (hypogammaglobulinemia, chronic inflammatory demyelinating polyneuropathy (CIDP), primary immunodeficiency diseases, myasthenia gravis, multifocal motor neuropathy, and other applications), and geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). The market report also covers the estimated market sizes and trends for 17 different countries across major regions, globally. The report offers the value (USD million) for all the above segments.