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Nucleic Acid Therapeutics Contract Development And Manufacturing Organization Market Analysis

The Nucleic Acid Therapeutics Contract Development And Manufacturing Organization Market size is estimated at USD 4.37 billion in 2024, and is expected to reach USD 8.88 billion by 2029, growing at a CAGR of 12.60% during the forecast period (2024-2029).

The market is growing, propelled by the increasing investment in developing nucleic acid therapeutics, complexities in manufacturing nucleic acid therapeutics, and the growing number of collaborations and partnerships with the market players. Complexities in manufacturing nucleic acid therapeutics, which require expertise in manufacturing like CDMO, are expected to drive market growth during the projected period. Manufacturing nucleic acid therapeutics presents unique challenges due to the intricate nature of these molecules and the need for precise, high-quality production. There are some complexities in nucleic acid therapeutic manufacturing, and CDMOs play a crucial role. Nucleic acid therapeutics, such as mRNA and antisense oligonucleotides, require precise synthesis of specific sequences.

CDMOs have specialized expertise and equipment for accurate and efficient synthesis. In addition, developing effective delivery systems, including lipid nanoparticles and viral vectors, is essential for ensuring the therapeutic reaches target cells. CDMOs have expertise in formulating and producing these carriers. Due to such complexities associated with the manufacturing of nucleic acid therapeutics, there is a need for CDMO expertise, thereby boosting the market growth between 2024 and 2029.

The increasing investment by the CDMO for expanding the CDMO facilities and services for nucleic acid therapeutics will likely boost the market from 2024 to 2029. For instance, Agilent Technologies Inc. announced that it will invest around USD 725 million to expand its manufacturing capacity for therapeutic nucleic acid. This investment is a testament to the high demand for therapeutic oligos and the exceptional quality and service of therapeutic oligo contract development and manufacturing organizations (CDMO). Additionally, in July 2023, Biovian announced a significant investment of over EUR 50 million (USD 52.7 million) to expand its manufacturing facility for viral vectors in Turku, Finland. Such high investment by the CDMO companies to develop the manufacturing facilities and services offering robust growth prospects are expected to propel the market during the projected period.

Additionally, rising partnerships and collaboration by the market players are expected to contribute to the market growth between 2024 and 2030. For instance, in January 2023, Charles River Laboratories International Inc. and Rznomics Inc. announced a viral vector contract development and manufacturing organization (CDMO) partnership. Rznomics will leverage Charles River’s viral vector CDMO experience to initiate clinical development of its RNA-based anticancer gene therapy in liver cancer patients. Similarly, in October 2022 and April 2022, BACHEM collaborated with Eli Lilly and Company to innovate and produce active pharmaceutical components derived from oligonucleotides, an emerging class of intricate nucleic acid treatments.

Hence, several complexities in manufacturing nucleic acid therapeutics, high investment costs, and market players' strategic collaboration are expected to boost the market between 2024 and 2029. Nevertheless, strict regulatory guidelines and insufficient expertise in nucleic acid therapeutics are expected to restrain the market.

Nucleic Acid Therapeutics Contract Development And Manufacturing Organization Market Trends

The mRNA Therapy Segment is Expected to Witness Significant Growth Between 2024 and 2029

Nucleic Acid Therapeutics Contract Development And Manufacturing Organization Industry Segmentation

The nucleic acid therapeutics CDMO market refers to the products and services provided by CDMO companies for manufacturing nucleic acid therapeutics. These therapeutics can be produced by either CDMO companies or pharmaceutical companies.

The nucleic acid therapeutics CDMO market is segmented by product type, application, end user, and geography. By product type, the market is segmented into cell and gene therapy, mRNA therapy, viral vector vaccines, plasmid DNA, antisense oligonucleotides, and siRNA therapy. By application, the market is segmented by oncology, genetic disorders, infectious diseases, and others. By end user, the market is segmented by pharmaceutical and biotechnology and government and academic research institutes. By geography, the market is segmented by North America, Europe, Asia-Pacific, Middle East and Africa, and South America. The report also covers the estimated market sizes and trends for 17 countries across major regions globally. The report offers the value (in USD) for the above segments.